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Simulate a single meal for a Type 2 diabetic. SimBiology Variant - Type 2 diabetic (inactive)ĬontentIndex: Type: Name: Property: Value:ģ6 parameter Basal Plasma G. We represented the insulin impairments in the SimBiology model as variant objects with the following names: Doing so made species units in amount or concentration, as required by SimBiology. Using a basis of 1 kilogram of body weight to transform species and parameters that were normalized by body weight in the original model. Setting the configuration set TimeUnits to hour, since simulations were conducted over 7 or 24 hours. (Note that SimBiology also supports the use of dimensionless parameters by setting their ValueUnits property to dimensionless.) (2007), which allows the SimBiology model to be simulated using unit conversion. Setting the units for all species, compartments, and parameters as specified by Dalla Man et al. Including an equation for the gastric emptying rate as presented in Dalla Man et al. Using the parameter values and initial conditions from the model equations and from Table 1 and Figure 1. Organizing the model into two compartments, one for glucose-related species and reactions (named Glucose appearance) and one for insulin-related species and reactions (named Insulin secretion). (2007) into reactions, rules, and events. Translating the model equations in Dalla Man et al.
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